Articles Tagged With: safety
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How Safe Is Cannabis for the Heart?
A nationwide Danish study of new prescriptions for medical cannabis for chronic pain compared to control patients has found that the 180-day incidence of atrial fibrillation/flutter is two-fold higher, but the absolute number of arrhythmias is small.
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Is Cannabis Abuse During Pregnancy Associated with Poor Neonatal Outcomes?
Cannabis use disorder is associated with small but significant increased risks measured in multiple neonatal outcomes.
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Daily Safety Call Improves Care at Hospital
A Maryland hospital found that a highly structured daily safety conference call with key clinicians and administrators can significantly improve patient safety. Attendees report safety issues, receive updates, and can act quickly on concerns.
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Safety and Tolerability of Inclisiran
A pooled analysis of seven relatively short-term ORION studies of inclisiran vs. placebo for lowering low-density lipoprotein cholesterol that assessed safety and tolerability for up to six years showed that inclisiran has similar rates of adverse events, excluding injection site reactions, as placebo treatment and is associated with fewer major adverse cardiovascular events.
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Atorvastatin vs. Rosuvastatin in Patients with Coronary Artery Disease
A large trial of moderate doses of rosuvastatin vs. atorvastatin in patients with coronary artery disease has shown that both drugs are equivalent at reducing major adverse cardiovascular and cerebral events, but rosuvastatin is associated with higher rates of new- onset diabetes and cataract surgery.
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Comparing the Safety of Cefepime and Piperacillin-Tazobactam: The ACORN Trial
Qian and colleagues conducted a pragmatic, open-label, randomized clinical trial to determine whether the empiric use of piperacillin-tazobactam or cefepime affects the risk of acute kidney injury (AKI) or neurological dysfunction in patients hospitalized for sepsis. The study showed no significant difference in the incidence of AKI between groups, but rates of neurological dysfunction were slightly higher in patients treated with cefepime.
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Young People Show Support for Social Determinants of Health Screening
Members of Generation Z appear willing to engage with clinicians about food security, housing, education, and more.
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Take Stock of Your Cybersecurity on Data Privacy Day
Part of building patient trust is ensuring personal information remains private and protected.
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Two Similar Studies, Two Different Conclusions: What Is the Best Way to Treat Sepsis?
The authors of two recent studies of the performance of the Epic Sepsis Model (ESM), a commonly used early warning tool for sepsis, reached different conclusions: One research group found ESM fails to predict many sepsis cases beyond what clinicians detect on their own, but another research group reported the tool enhances care.
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IRBs Scrutinizing Recruitment of Adolescents via Social Media
When recruiting adolescents online, investigators should think about how they would proceed if recruitment was conducted in person. Researchers would not be able to barge into an in-person group meeting without an invitation, just as they cannot post in a private Facebook group without the moderator’s permission.