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Articles Tagged With: systolic

  • New RNA Interference-Based Therapy for Hypertension

    A randomized, double-blind, placebo-controlled trial of a range of doses of a new ribonucleic acid (RNA) interference drug that reduces hepatic angiotensinogen levels has shown significant mean 24-hour systolic blood pressure reductions at three months after a single subcutaneous injection.

  • Blood Pressure Management After Endovascular Thrombectomy: What Is the Best Number?

    Approximately 50% of patients who undergo endovascular therapy for ischemic stroke still have a severe impairment or will die within 90 days. Therefore, additional interventions are being investigated to improve overall outcome. Current guidelines from the American Heart Association suggest maintaining systolic blood pressure below 180 mmHg for patients who were treated both with intravenous thrombolysis and endovascular thrombectomy. A number of centers around the world have tried different systolic blood pressure thresholds ranging from 120 mmHg to 160 mmHg. Many of these studies have been single-center or small non-randomized studies and have not been designed to get a definitive answer.

  • Hypertension in Adults: An Update

    Hypertension remains the leading cause of death and disability-adjusted life years globally, accounting for 10.4 million deaths per year. In the United States, hypertension accounts for more cardiovascular disease deaths than any other modifiable risk factor and is second only to cigarette smoking as a preventable cause of death for any reason.

  • Blood Pressure and Brain Lesions: Is There a Connection?

    Reducing blood pressure in elderly patients could lower risk for development of lesions.

  • Systolic and Diastolic Heart Failure

    Acute decompensated heart failure is a serious condition that presents in the emergency department and the intensive care unit. The causes of heart failure are multifactorial, making it, at times, difficult to diagnose and treat.