Articles Tagged With: therapy
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Can Bariatric Surgery Control Blood Pressure Long-Term?
A randomized trial comparing bariatric surgery to medical therapy in hypertensive obese patients has shown that bariatric surgery effectively lowers blood pressure over five years of follow-up.
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New RNA Interference-Based Therapy for Hypertension
A randomized, double-blind, placebo-controlled trial of a range of doses of a new ribonucleic acid (RNA) interference drug that reduces hepatic angiotensinogen levels has shown significant mean 24-hour systolic blood pressure reductions at three months after a single subcutaneous injection.
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Long-Term Antiplatelet Therapy After PCI
The five-year follow-up of patients randomized to clopidogrel vs. aspirin monotherapy beyond one year after percutaneous coronary intervention has shown that clopidogrel is noninferior, but not superior, to aspirin for preventing the combined endpoint of adverse cardiovascular or major bleeding events.
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Zuranolone Therapy for Depression in the Postpartum Period
Zuranolone was well tolerated and resulted in substantial improvement of depressive symptoms in the postpartum period, suggesting that it may be a promising new oral therapy for postpartum depression.
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A Comparison of Acute Migraine Therapies Using Big Data
In a big data-driven observational study that compared 3 million treated migraine attacks captured from a migraine diary smartphone app, triptans were found to be the most efficacious treatment class. Among the triptans, eletriptan had the highest rate of success. Consistent with clinical practice and recent consensus statements, the success of triptans was followed by ergots and antiemetics.
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A Comparison of Acute Migraine Therapies Using Big Data
In a big data-driven observational study that compared 3 million treated migraine attacks captured from a migraine diary smartphone app, triptans were found to be the most efficacious treatment class. Among the triptans, eletriptan had the highest rate of success. Consistent with clinical practice and recent consensus statements, the success of triptans was followed by ergots and antiemetics.
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Exagamglogene Autotemcel Suspension (Casgevy)
The U.S. Food and Drug Administration has approved the first treatment for sickle cell disease using CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 (CRISPR associated protein 9) genome editing technology.
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Who Benefits Most from Tirzepatide Among Patients with Type 2 Diabetes?
Females, patients of white or Asian race, younger patients, and those taking metformin benefit the most from treatment with tirzepatide.
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Anti-Ischemic Therapy for Microvascular Angina
A small, invasive study of coronary microvascular disease patients has shown that those with a coronary flow reserve < 2.5 may benefit from anti-ischemic therapy.
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Which Coronary Artery Calcium Score Signifies the Need for Secondary Prevention?
A large registry study of individuals without known cardiovascular disease but with known coronary artery computed tomography calcium scores showed those with an Agatston score higher than 300 are at risk of experiencing major cardiac events similar to patients with known cardiovascular disease over five years.