Articles Tagged With: tranexamic
-
Tranexamic Acid in Patients with Intracerebral Hemorrhage Does Not Improve Outcomes
Primary intracerebral hemorrhage is a major cause of severe neurological disability and carries a high rate of death. Tranexamic acid was tested in a study of 2,325 patients with intracerebral hemorrhage within eight hours of symptom onset, but did not significantly improve neurological outcome.
-
Tranexamic Acid and Outcomes in Patients with Moderate or Severe TBI
In this randomized, placebo-controlled trial using tranexamic acid to treat patients with moderate or severe traumatic brain injury within two hours of injury, there was no significant difference between treatment groups in either mortality or functional recovery at six months.
-
Update on Postpartum Hemorrhage
In the United States, postpartum hemorrhage accounts for 11.4% of maternal deaths, the fourth most common cause after cardiovascular diseases, non-cardiovascular diseases, and infection; worldwide, it is the leading cause of maternal mortality. This feature will discuss the latest treatments for managing postpartum hemorrhage.
-
Tranexamic Acid in Trauma
Tranexamic acid or TXA is a potent antifibrinolytic that has the potential to decrease clot breakdown and reduce bleeding in trauma patients. Studies have shown that the use of TXA in trauma patients improves overall survival, although these studies have been discounted as not being relevant to trauma care as practiced in well-resourced countries. Thus, the adoption of TXA into trauma protocols in U.S. centers has been slow and controversial. Further studies are needed to answer questions about which patient populations can benefit most from TXA and how it should be used in highly developed and well-resourced trauma systems and centers.
-
Tranexamic Acid-associated Seizures: Features, Mechanisms, and Treatment
Tranexamic acid is a commonly used antifibrinolytic drug that has been associated with increased risk of postoperative seizures. The authors reviewed the incidence, risk factors, and clinical features of these seizures, as well as potential mechanisms. They also proposed treatments and interventions for preventing Tranexamic acid-related seizures.