Psilocybin Produces Long-Term Antidepressive Benefits

Some patients sustained positive effects up to one year after treatment.

Noncompliance with Sepsis Measures Used to Prove Care Was Negligent

Along with growing general awareness, there are several positive developments in ED sepsis care, including laboratory tests helpful in diagnosing sepsis cases that have improved substantially. Also, there are new biomarkers of sepsis that are promising, and new molecular tests allow a lab to identify blood-borne infections in hours instead of the days formerly required for blood cultures to grow.

As Opioid Epidemic Continues Unabated, EDs Mobilize to Save Lives

Investigators have made remarkable progress in identifying patients with opioid use disorder when they present to the ED, and convincing frontline providers to initiate these patients on medication-assisted treatment. Further, they have been regularly documenting their ongoing improvement efforts to offer other EDs a potential roadmap for how to improve in this area and sustain that progress.

Unique Ethical Issues with Research on Difficult-to-Treat Depression

Researchers should focus on these three areas: How to define this group of patients, which is heterogenous; how to acquire and interpret clinically meaningful outcome metrics; and how to design clinical trials to promote generalizability.

Treating Opioid Use Disorder Could Lower Recidivism Rates

Giving inmates buprenorphine helped them avoid new court charges, probation violations, and reincarceration.

Midurethral Slings for the Management of Stress Urinary Incontinence

The controversy surrounding polypropylene mesh use has confused and discouraged women from seeking surgical treatment for stress urinary incontinence. Midurethral slings remain the standard of care for the surgical treatment of stress urinary incontinence.

Few EDs Screen Patients for Excessive Alcohol Use

The ED is where patients often go during their most vulnerable times. Emergency providers can help vulnerable patients prevent a future crisis if they can show patients that help is available and how to access it.

ED Visits for Alcohol and Substance Use Disorders Surging Nationally

Presentations often are bundled with a host of comorbid conditions and chronic or acute traumatic events. Providers should suspect and expect an underlying potentially serious coexisting medical complication in each patient encountered until proven otherwise.

Fluvoxamine Reduces the Risk for Hospitalization from COVID-19

A randomized, placebo-controlled trial found fluvoxamine (100 mg twice a day for 10 days) reduced the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.

Resistance Erodes Standard Treatment for Pneumonia

These data suggest community-acquired pneumonia CAP therapy may no longer be relevant for many patients with CAP, and the required use of the current CAP bundle with limited antibacterial therapy choices should be re-assessed.

Articles Tagged With: treatment