Cancer patients undergoing treatment are immunocompromised and at high risk for developing early complications leading to critical illness. Compared to complications encountered with conventional chemotherapy, new-generation immunotherapies pose unique diagnostic challenges because their presentation can be vague and nonspecific or can mimic autoimmune diseases.
Influenza is an acute respiratory illness responsible for significant seasonal epidemics each year. Despite commonly being a self-limited illness, the virus causes significant morbidity and mortality. During the winter months, emergency physicians should maintain a high suspicion for influenza in patients presenting with an acute febrile respiratory illness.
Investigators evaluated 135 patients with Staphylococcus aureus bacteremia (SAB) in a prospective cohort study comparing early switch to oral linezolid to continued treatment with standard parenteral therapy (SPT). Patients with complicated SAB and osteoarticular infection were excluded. Early switch to oral therapy yielded similar outcomes to continued SPT and allowed earlier hospital discharge.
In glucose-6-phosphate-dehydrogenase-sufficient individuals in Southeast Asia, combined treatment with chloroquine and primaquine provides much more lasting relief from vivax malaria than either chloroquine alone or artesunate.
Although many cases of extremity pain are the result of mild, self-limited issues, ischemia and gangrene are catastrophic causes of pain that initially can present with nondescript findings. To limit tissue loss and optimize patient outcomes, emergency physicians must be able to distinguish benign limb pain from the earliest stages of high-risk, life- and limb-threatening disease.
Since 2006, the Centers of Disease Control and Prevention has recommended the use of expedited partner therapy (EPT) for treatment of sexually transmitted infections such as gonorrhea and chlamydia, but the infection rate continues to climb.
Sexual function often decreases for women because of the genitourinary syndrome of menopause (GSM). This condition includes the physical changes of the vulva, vagina, and lower urinary tract that result from estrogen deficiency.
This article reviews the current status of expedited partner therapy (EPT), which involves treating the heterosexual partners of patients diagnosed with chlamydia or gonorrhea by providing the medication or a prescription for the patient to give to the partner without a healthcare provider first examining the partner.