What do you see as three of the most important reproductive health advances of the past 25 years?

In the field of sexually transmitted diseases [STDs]: development of noninvasive STD testing methods (predicated upon molecular biologic techniques; development of syndromic management for STDs in some developing country settings; and development of transmission dynamics concepts, permitted in part by advances in mathematical modeling.�
� Stuart Berman, MD, chief of the epidemiology and surveillance branch in the Atlanta-based Centers for Disease Control and Prevention�s division of STD prevention

�The most important advances in the last 25 years in reproductive health include the development of and increasing access to mifepristone and medical abortion broadly; the broader range of delivery mechanisms for hormonal contraception, such as the patch, ring, and implants, and emergency contraception.�
Kelly Blanchard, president of Ibis Reproductive Health in Cambridge, MA

�I would suggest the three most important advances are the availability of medical abortion, the mainstreaming of emergency contraception, and the growth in condom use, especially by adolescents. If only technology, I�d pick the shift from dilation and curettage [D&C] to vacuum aspiration abortion.�
Sharon Camp, president of the Alan Guttmacher Institute in New York City

�In the field of sexually transmitted infections, the most important for diagnosis and treatment include polymerase chain reaction technology for easier screening, the development of acyclovir, and HIV antiretroviral drugs.�
Ward Cates Jr., MD, MPH, president/chief executive officer of the Institute for Family Health at Family Health International in Research Triangle Park, NC

�Medical abortion, the levonorgestrel intrauterine system, and alternative delivery systems for contraceptive steroids, such as the patch, ring, and implant.�
David Grimes, MD, vice president of biomedical affairs at the Institute for Family Health at Family Health International in Research Triangle Park, NC

�Assisted reproductive technologies must rank very highly. It of course has created problems, but the amount of new knowledge gained will ultimately lead to progress with even better methods of contraception. Induced abortion by medical treatment is a tremendous step forward, especially in the developing world.

�The contribution to worldwide family health is enormous. It is very important that we have established the safety of estrogen-progestin contraception. The combined safety of lower doses and better patient screening by informed clinicians now makes serious side effects almost totally avoidable.�
Leon Speroff, MD, associate director of the Women�s Health Research Unit at Oregon Health & Science University in Portland

�Different ways of delivering hormones is one of the greatest steps forward. Now that we know more about their safety and health benefits, it is also wonderful to be able to offer hormonal methods like the patch, the ring, the intrauterine system, injections, and soon a new one-rod implant. These options give women greater flexibility to find the method that best meets their needs.
Susan Wysocki, RNC, NP, president and chief executive officer, Association of Nurse Practitioners in Women�s Health in Washington, DC

�The three things I see as most important are the lowering of the dose of ethinyl estradiol in combination hormonal contraception; the development of�novel and more effective contraceptive options for women, such as the injectable, newer intrauterine devices, the patch, the vaginal ring, and Essure [transcervical sterilization]; and the development of mifepristone.
Edio Zampaglione, MD, director of contraception at Organon Pharmaceuticals USA in Roseland, NJ

 

What three advances do you see in the next five to 10 years when it comes to contraception and reproductive health?

�Male contraception; new female-controlled HIV/STD prevention technologies; and freer access to contraceptives.�
� Blanchard

�In the coming years, the biggest advances could be the emergence of safe and effective vaginal microbicides; the widespread availability of pre-natal genetic testing; and simple, reliable home tests for common STDs.�
� Camp

�Over-the-counter availability of emergency contraception; availability of a single rod contraceptive implant, offering easier and faster insertion/removal than with multiple implant systems; and availability of lower-dose depot medroxyprogesterone acetate [DMPA] formulation administered by the subcutaneous route, which should facilitate DMPA self-administration.�
Andrew Kaunitz, MD, professor and assistant chair in the obstetrics and gynecology department at the University of Florida Health Science Center/Jacksonville

�The three advances I see are development of highly effective nonsteroidal methods of contraception,(not barrier methods or locally applied gels/creams/films; development of a contraceptive that offers high efficacy along with sexually transmitted disease [STD] protection (unlike the condom); and development of a male contraceptive that is not coital-dependent.
� Zampaglione