Neurology Alert – July 1, 2024
July 1, 2024
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Intensive Lifestyle Interventions May Prevent and Ameliorate the Symptoms of Alzheimer’s Disease
Recent clinical studies support the benefit of intensive lifestyle interventions, which should include a plant-based diet, exercise, stress management, and avoidance of smoking and alcohol, for the prevention of Alzheimer’s disease.
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Usefulness of the Physical Examination in the Concussed Patient
This article suggests that certain specific physical examination findings may be helpful in evaluating and monitoring patients with sports-related concussion using oculovestibular responses and balance tests.
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Efgartigimod for Seronegative Myasthenia Gravis
In an uncontrolled, open-label series of patients with myasthenia gravis, double antibody-negative patients responded to immunosuppressive therapies in a similar manner as do those with antibodies to acetylcholine receptors (AChR) or muscle-specific tyrosine kinase. However, when treating myasthenia patients with a specific agent (efgartigimod) that blocks AChR antibodies at the level of endothelial cells, double antibody-negative patients do not respond as well.
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Disorders of Immunity Are a Risk Factor for Herpes Simplex Virus Encephalitis
The current study of herpes simplex virus (HSV) encephalitis demonstrated an association of encephalitis with preexisting autoimmune disease and/or exposure to immunosuppressive and immunomodulatory medications. The findings underscore the potential underestimation of antecedent immune-related dysregulation in HSV encephalitis cases to date.