Five hundred twenty-four children and adults with either cellulitis or abscesses larger than 5 cm (smaller for children) were enrolled in a multisite prospective study of clindamycin vs. trimethoprim-sulfamethoxazole dosed for 10 days. Cure rates did not differ between the treatments, and rates of adverse events were similar in the two groups.
An observational cohort study found that rectal colonizing strains of E. coli are the source for most fluoroquinolone-resistant post-transrectal prostate biopsy infections. Pre-procedure screening cultures should be considered.
Two thousand six hundred thirty-eight children with a clinical diagnosis of community-acquired pneumonia (CAP) were enrolled in a prospective surveillance study. Eighty-nine percent had radiographic evidence of pneumonia. The median age of children hospitalized was 2 years, with the highest rates seen in children younger than 2 years. Respiratory viruses were the most commonly detected pathogens.
Physicians can improve the health of unaccompanied Central American immigrant children by ensuring appropriate vaccination, by identifying culturally and linguistically appropriate community resources, and by becoming involved in patient advocacy.