A retrospective observational study found that among hospitalized patients, ward-level antibiotic prescribing was associated with a significantly increased risk for C. difficile infection beyond what would be expected with patient-level antibiotic use.
A large study of HPV vaccination among girls 13-14 years of age demonstrated significant reduction of cervical dysplasia that was detectable by 17 years of age, providing justification for not delaying HPV vaccination in girls until older adolescence.
Whether based on history, tachypnea, or X-ray findings, the diagnosis of pneumonia in children is incompletely accurate. Ultrasound is a reasonable alternative tool for the diagnosis of childhood pneumonia.
The high negative predictive value of a negative nasal screen for methicillin-resistant Staphylococcus aureus suggests these patients do not have lower respiratory tract infections caused by the organism.
Although potential benefit may have been detected in a post hoc subset analysis, the addition of anidulafungin in the initial phase of primary treatment of suspected or documented invasive aspergillosis was not associated with a significant improvement in survival.