Infectious Disease Alert – August 1, 2015
August 1, 2015
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Antibiotics for Acute Appendicitis
ABSTRACT & COMMENTARY: Of those who needed surgery after treatment with antibiotics, the risk for complications was low.
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Polio — New Strategies as We Get Close to Eradication
The switch to a bivalent live attenuated oral polio vaccine by elimination of serotype 2 will be coordinated with the use of trivalent inactivated vaccine. The goal is to eliminate outbreaks of polio due to vaccine serotype 2, the major cause of such events.
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BCG — Back to the Future?
In a population-based study, neonatal vaccination with bacille Calmette-Guérin significantly reduced rates of hospitalization for non-tuberculous respiratory infection and sepsis. BCG vaccine might provide significant protection through nonspecific immune enhancement.
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Does Bacteremia Associated with Bone and Joint Infections Require Prolonged IV Antibiotic Therapy?
Two hundred sixty-five children with culture-proven acute bone or joint infections were studied. All patients received 2-4 days of IV antibiotics followed by PO antibiotics. Clinical outcomes and resolution of inflammatory biomarkers were the same whether the patient had positive blood cultures or not on admission.
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When Profiling Is a Good Thing: Distinguishing Bacterial from Viral Infection
Transcriptional analysis outperformed serum procalcitonin in distinguishing viral from bacterial infections.
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Decreasing Cross-Transmission of Carbapenemase-Producing Enterobacteriaceae
A bundled infection control intervention was shown to decrease cross-colonization, prevalence, and bloodstream infection of Klebsiella pneumonia carbapenemase-producing Enterobacteriaceae in long-term acute care hospitals, which may have far-reaching effects into the ICU.
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Squirrels as the Source of a New Viral Cause of Encephalitis
Evidence indicates that a newly discovered bornavirus caused infection in squirrels and was transmitted from them to three humans who developed encephalitis and died.
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Infectious Disease Alert Updates
HPV on that Ultrasound Probe? and Saving Elephants from Herpesviruses