– January 1, 2005
January 1, 2005
View Archives Issues
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Capecitabine and Vinorelbine in Elderly Patients (Older than 65 years) with Metastatic Breast Cancer
This regimen of capecitabine and vinorelbine is well tolerated and effective in elderly patients with metastatic breast cancer. Toxicity was mainly hematological and was observed at a lower dose in patients with bone involvement. A phase II study with the 2 different dose levels for elderly patients with and without bone involvement is currently being conducted. -
Efficacy of a Bivalent L1 Virus-Like Particle Vaccine in Prevention of Infection with Human Papillomavirus Types 16 and 18 in Young Women
The bivalent HPV vaccine was efficacious in prevention of incident and persistent cervical infections with HPV-16 and HPV-18, and associated cytological abnormalities and lesions. Vaccination against such infections could substantially reduce incidence of cervical cancer. -
Raloxifene and Breast Cancer: The CORE Study
Raloxifene treatment of postmenopausal women with osteoporosis is associated with a lower incidence of estrogen receptor-positive invasive breast cancer. -
Chemotherapy Sensitivity/Resistance Assays in Gynecologic Cancer: Are We There Yet?
Over the last few decades, technology has existed to evaluate the cytotoxic effects of single-agent and combination chemotherapy on cancer cell lines derived from an individual patient's tumor specimens. However, investigators and clinicians have been frustrated as the fruit of this technologya reliable and reproducible assay to help them treat their patients with the agent or agents most likely to benefit themhas yet to be proven. -
Attention Readers...
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Pharmacology Watch: Hypertension: Therapy vs Calcium Channel Antagonists
GEMINI Trial, CAMELOT Trial, INVEST Trial, The Dangers of Vitamin E, FDA Actions. -
Clinical Briefs in Primary Care supplement