A 67-year-old previously healthy man was referred from his primary care physician because of an abnormal CBC. Although he had noted gradually increasing fatigue over approximately six months, this had become noticeably worse and, for this reason, he went to the doctor. He had not experienced night sweats or weight loss and had no localizing symptoms.
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Approximately half of colon cancer patients will develop liver metastases during the course of their disease, but only about 20% of patients with hepatic metastases are candidates for surgical resection.
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Within a large series of colorectal cancer patients receiving initial chemotherapy, a prompt rise and then drop in CEA level (flare) was observed in 11.6%. Compared with patients who had a continuous rise in CEA, those exhibiting a flare reaction had improved response to chemotherapy and progression-free and overall survival.
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Invasive aspergillosis remains a problematic complication of therapy. The authors prospectively evaluated IA infections among AML patients at 21 centers.
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Fractures and bisphosphonate therapy, warfarin anticoagulation and influenza vaccine and cotrimoxazole, antiplatelet therapy with clopidogrel and aspirin, FDA Actions.
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