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    Home » Newsletters » Neurology Alert

    Neurology Alert

    www.reliasmedia.com

    February 1, 2019

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    As a valued Relias Media subscriber, you can find the latest issue of your publication online. The articles below provide timely strategies and research for healthcare providers:

    Continuous EEG Monitoring in Critically Ill Patients Is Associated With Reduced Hospital Mortality

    In this retrospective cross-sectional study involving more than 7 million critically ill adult patients from the National Inpatient Sample database, researchers showed that the use of continuous electroencephalography is associated with lower in-hospital mortality.

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    Rituximab for CIDP Associated With Systemic Immune Disorders

    Rituximab has been used “off label” for the treatment of primary chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) with variable reports of success. These authors reported a high rate of response in patients who developed CIDP in the setting of other systemic immune-mediated disorders.

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    Amyloid-ß Pathology Induced by Contaminated Cadaver-Derived Growth Hormone

    Cadaveric pituitary-derived growth hormone that previously was known to transmit Creutzfeldt-Jakob disease (CJD) also contains ß-amyloid. Growth hormone vials from cases associated with amyloid plaques in CJD patients cause amyloid plaque formation and cerebral amyloid angiopathy when injected intracranially into mice.

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    Predicting the Risk of Mild Cognitive Impairment Using Imaging Biomarkers

    In this population-based study, researchers used imaging biomarkers of amyloid and neuronal injury to estimate an absolute risk of mild cognitive impairment in the elderly.

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    Thinking Outside of the ‘Alpha-Synuclein Box’: A Critical Role of Tau in Lewy Body Disorders

    Neocortical tau pathology was associated with worse antemortem cognition in this large study of Parkinson’s disease dementia and dementia with Lewy bodies. Regional brain variations correlated with specific cognitive domains.

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    Neurology Alert

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    Neurology Alert (Vol. 38, No. 6) - February 2019
    February 1, 2019

    Table Of Contents

    Continuous EEG Monitoring in Critically Ill Patients Is Associated With Reduced Hospital Mortality

    Rituximab for CIDP Associated With Systemic Immune Disorders

    Amyloid-ß Pathology Induced by Contaminated Cadaver-Derived Growth Hormone

    Predicting the Risk of Mild Cognitive Impairment Using Imaging Biomarkers

    Thinking Outside of the ‘Alpha-Synuclein Box’: A Critical Role of Tau in Lewy Body Disorders

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    Financial Disclosure: Neurology Alert’s Editor in Chief Matthew Fink, MD; Peer Reviewer M. Flint Beal, MD; Executive Editor Leslie Coplin; Editor Jonathan Springston; and Editorial Group Manager Terrey L. Hatcher report no financial relationships relevant to this field of study.

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