Steroid Treatment Regimens for Chronic Inflammatory Demyelinating Polyneuropathy

In the United States, first-line treatment for chronic inflammatory demyelinating polyneuropathy (CIDP) is intravenous immunoglobulin (IVIG). Authors of this retrospective survey from Europe found that corticosteroid treatment had similar efficacy as IVIG and should be considered as first-line therapy for CIDP.

Ibudilast Shows Promise for the Treatment of Progressive MS

A Phase II trial of ibudilast in progressive multiple sclerosis demonstrated a decreased rate of brain atrophy when compared to placebo.

Cerebellar Atrophy May Contribute to Cognitive Impairment in FTD

In this cross-sectional study, researchers identified distinct patterns of cerebellar atrophy and its association with cognitive dysfunction in the frontotemporal dementia syndromes.

Primary Headaches: Look, Listen, and Diagnose Rather Than Image

SYNOPSIS: The diagnosis of primary headache disorders by a computerized and clinical paradigm can predict a baseline prevalence of intracranial abnormalities on brain imaging. Some historical “red flags” in children with headaches, including morning headaches and occipital pain, are not associated with increased intracranial abnormalities.