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Multiple clinical tools have emerged to assess small fiber nerve dysfunction, but validated diagnostic criteria are needed to optimize diagnostic sensitivity, support clinical management, and facilitate patient selection for clinical trials.
Anterior interosseous nerve syndrome is part of the median neuropathy spectrum and often has been attributed to compression near the elbow. Modern magnetic resonance neurography and ultrasound studies have ruled-out compression in most cases.
In this prospective, population-based study, mean lifetime heritability of amyotrophic lateral sclerosis was 52% in the entire cohort and 37% in patients devoid of any known pathogenic mutations. The highest heritability was seen in mother-daughter parings in both groups.
Accumulating evidence suggests that immune dysregulation by glioblastoma cells induces tumor-associated edema and that disruption of this tumor-immune interaction may represent a novel strategy to reduce cerebral edema in glioblastoma.
Therapeutic hypothermia is beneficial and increases the probability of brain recovery in patients with coma due to cardiac arrest with a nonshockable heart rhythm.
Financial Disclosure: Neurology Alert’s Editor in Chief Matthew Fink, MD; Peer Reviewer M. Flint Beal, MD; Editorial Group Manager Leslie Coplin; Editor Jason Schneider; Executive Editor Shelly Morrow Mark; and Accreditations Manager Amy M. Johnson, MSN, RN, CPN, report no financial relationships relevant to this field of study.
