OB/GYN Clinical Alert – March 1, 2015
March 1, 2015
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Weight Gain with Contraception
In this prospective cohort study, perceived weight gain was found to be an adequate predictor of actual weight gain. Depot medroxyprogesterone acetate and the contraceptive implant were associated with more weight gain than the copper IUD. -
Intercourse at the Time of Implantation Confers Lower Chance of Conception
Couples attempting natural conception were found to have a lower chance of success per cycle when intercourse took place at or around the time of implantation. -
Delayed Cord Clamping
Although a recent study has failed to show major benefit from delayed umbilical cord clamping, others have suggested neonates having delayed cord clamping have less need for transfusion, higher hematocrits, less neonatal morbidity, and diminished risk of intraventricular hemorrhage. -
Endometrial Protection: Which Progestogen Is Best?
After a lost decade, increasing numbers of women and providers are recognizing the benefits of postmenopausal hormonal therapy. For women with an intact uterus, endometrial protection is required when systemic estrogen therapy is used. Since activity at the glucocorticoid and androgen receptor may lead to adverse health effects in some women, use of pure progesterone receptor agonists may offer advantages. However, the use of natural progesterone is problematic due to low potency and poor bioavailability with oral dosing. Local therapy with the levonorgestrel intrauterine device (off-label) may be an excellent choice for many women.