AIDS Alert Archives – May 1, 2006
May 1, 2006
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Truvada trials hold promise for new HIV prevention strategy
Researchers and public health officials say they hope ongoing research will eventually show efficacy with a new prevention strategy that involves giving uninfected people at risk for HIV a simple combination reverse transcriptase inhibitor (RTI) therapy. -
A completely new target for fighting HIV infection?
Investigators have discovered a natural host defense against HIV thanks to a little help from yeast virus research. Researchers have found that two DNA repair genes can defend cells from HIV infection. -
Metabolic problems in children on ARTs found
Conducting clinical trials involving HIV-infected children is very challenging, so the evidence has slowly trickled in, but researchers now believe HIV infection among children can lead to similar metabolic and other problems long noted in adults with the disease. -
Research findings suggest new course against HIV
New research provides some answers to long-standing questions about how HIV proliferates despite the initial strong immune response. Investigators have discovered evidence that HIV-1 evades some immune cell responses by hijacking physiological feedback inhibitors in B cells via the negative factor (Nef) protein, an HIV-1 protein that is expressed by infected cells. -
Adherence Strategies: Therapy for family, patient improves adherence
Investigators have found that an intensive one-on-one therapy that involves HIV patients and their families holds promise as an effective adherence intervention. -
DM program keeps AIDS patients out of hospital
An intensive one-on-one case management program helps people with AIDS stay adherent to their medication regime, avoid hospitalizations and emergency department visits, and learn to self-manage their disease. The disease management program of the AIDS Healthcare Foundation, received a score of 98.4% out of a possible 100% during the survey. -
HIV subtype efficient mortality predictor
A surprising finding from the research-rich Rakai (Uganda) cohort shows that a persons HIV subtype is a significant predictor of whether a person might die quickly from AIDS than viral load, CD4 cell count, and other common predictors of disease progression.