Azithromycin therapy failed in a patient in San Francisco with a primary syphilitic chancre which subsequently resolved after administration of a single dose of benzathine penicillin. Sequencing of the 23S rRNA genes of Treponema pallidum from 2 San Francisco patients who had failed azithromycin therapy revealed the presence of a mutation identical to that previously associated with macrolide resistance in a single isolate (T. pallidum, Street 14 strain).
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An outbreak of food poisoning by Yersinia pseudotuberculosis in Finland in October/November 1998 involved 46 cases and was traced to locally grown iceberg lettuce.
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A number of readers may be aware of reports of 2 agents being used on the battlefield in Iraq QuikClot and HemCon. Alam and colleagues report a study that compares these agents, plus others, in a swine model of uncontrolled hemorrhage.
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