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To date, the annual physical has shown minimal, if any, benefit and potential for harm.
Omission of breakfast was associated with less secretion of insulin and glucagon-like peptide and higher levels of free fatty acids, glucose, and glucagon.
Total knee replacement provides better outcomes for pain, symptoms, activities of daily living, and quality of life than medical therapy alone.
The recognition that incretin secretion is impaired in type 2 diabetes stimulates consideration of a similar trial in diabetic patients.
After successful healing of an ankle fracture, a program of supervised physical therapy does not appear to improve outcomes.
Although the rate of distant recurrence and breast cancer mortality were statistically and significantly superior in women who had been treated with bisphosphonates, the absolute degree of benefit was of dubious clinical relevance.