In patients on venovenous extracorporeal membrane oxygenation for acute respiratory distress syndrome, prone positioning is safe and feasible. Prone positioning appears to improve survival but increases length of stay.
When requests for potentially inappropriate treatments occur, the initial steps include increasing communication and improving mutual understanding to find a path that is appropriate while honoring the goals and concerns expressed by patients and their families.
In this randomized clinical trial, hypertonic saline given via rapid intermittent bolus therapy was as effective and safe as slow continuous infusion, and was associated with a lower rate of recorrecting treatment and higher efficacy in achieving goal sodium within one hour.
By shortening the duration of antibiotic therapy, a procalcitonin-guided protocol decreased the rate of infection-associated adverse effects, decreased costs, and reduced mortality in patient with sepsis.
Using semi-structured interviews with intensive care unit (ICU) survivors and their family members, investigators identified several ICU processes of care and outcomes after the ICU that were important to this population.
This retrospective analysis compared historical cohorts with COVID-19-related acute respiratory distress syndrome (ARDS) with respect to compliance and arterial partial pressure of oxygen/fraction of inspired oxygen (P/F) ratios. For comparable P/F ratios, patients with ARDS caused by COVID-19 had higher lung compliance and more lung gas volume.
Post-hoc analysis of a multicenter, randomized clinical trial among adults receiving at least 24 hours of mechanical ventilation who were ready for ventilator weaning revealed that the use of pressure support significantly increased the proportion of patients successfully extubated compared to T-piece.