This large-scale review study brings promising direction to the field; understanding the effect of specific musical interventions on specified outcomes could and should lead to a more targeted and efficacious approach.
Among a group of ischemic stroke patients last known to be well six to 24 hours earlier and who had a mismatch between clinical deficit and infarct size, outcomes regarding disability and functional independence were better if treated with mechanical thrombectomy, rather than standard care alone.
This study affirmed that giving allied health professions autonomy to execute care within well-structured, supervised protocols/guidelines is an efficient solution to many of the current obstacles in providing patient care in an increasingly fractured environment.
With an aging population and growing numbers of ICU beds, the question arises as to whether the ICU truly is beneficial for this vulnerable population. To explore this question, a cluster-randomized, clinical trial was designed to determine whether a method of systematic ICU admission in critically ill elderly patients reduced six-month mortality.
Not only does ordering routine follow-up blood cultures in patients with GNR bacteremia seldom produce helpful information, but common false-positive results can lead to longer length of stay, additional inappropriate antibiotic therapy, and increased healthcare costs.
Compared to the ARDSNet lower positive end-expiratory pressure (PEEP)/low tidal volume strategy, use of an “open lung ventilation” strategy consisting of aggressive alveolar recruitment maneuvers and higher PEEP is associated with higher mortality in patients with moderate to severe acute respiratory distress syndrome.
In this sham-controlled trial of 200 patients with single-vessel coronary artery disease and stable angina, percutaneous coronary intervention did not increase exercise time significantly compared to a placebo procedure.
A large nationwide comprehensive clinical database showed that concomitant use of the new oral anticoagulants with amiodarone, fluconazole, rifampin, and phenytoin increases the risk of major bleeding.