Infectious Disease Topics
RSSArticles
-
Delusional Infestation
Delusional infestation, previously known as delusional parasitosis, is a condition with which patients believe that their bodies are infested with abnormal living organisms or non-living substances. Many patients can recover with a good therapeutic clinician-patient relationship and, usually, the use of risperidone, aripiprazole, or olanzapine.
-
Mortality in Sepsis Patients Treated with Piperacillin-Tazobactam vs. Cefepime
A retrospective cohort study that included more than 7,000 patients with sepsis and no clear indication for anti-anaerobic coverage found receipt of piperacillin-tazobactam was associated with higher mortality and increased duration of organ dysfunction compared to cefepime.
-
Infectious Disease Alert Updates
Pushing for STI Testing in Those at Risk; TB Screening Dismayingly Low in Those at Risk
-
Varicella Zoster Meningitis — What Is the Optimal Therapy?
The authors concluded that their results indicate a need for controlled trials comparing intravenous acyclovir to valacyclovir or to no antivirals in the management of varicella zoster meningitis without neurological complications in immunocompetent patients.
-
Dengue Is Surging, Including in the Americas
Dengue is surging, and cases have been acquired in the United States, including in Puerto Rico and Florida.
-
Beta-Lactam Antibiotics Administered via Prolonged Infusions Lead to Lower Mortality Risk Compared to Intermittent Infusions
In a systematic review and meta-analysis, the administration of beta-lactam antibiotics by prolonged infusions was associated with a significantly reduced risk of mortality at 90 days for critically ill patients with sepsis or septic shock as compared with intermittent infusions.
-
Doxycycline for Onchocerciasis-Related Epilepsy?
Nodding syndrome is a form of pediatric encephalopathy with epilepsy that is associated with Onchocerca volvulus infection in children in Africa. While the pathogenesis is not known, doxycycline helps reduce severe seizures and death in children with nodding syndrome.
-
Antibiotic De-Escalation Can Decrease the Development of Antibiotic Resistance in Gram-Negative Bacteria
A retrospective cohort study found that de-escalation of broad-spectrum beta-lactam agents in patients with sepsis significantly reduced the subsequent development of antimicrobial resistance in gram-negative bacteria isolated from clinical cultures.
-
Doxycycline After Sex
Single-dose doxycycline is recommended after oral, vaginal, or anal sex in selected high-risk individuals.
-
Cefepime and Enmetazobactam Injection (Exblifep)
The U.S. Food and Drug Administration has approved the combination of cefepime and enmetazobactam (FPE) for the treatment of complicated urinary tract infections (cUTIs).