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Olesen and associates report on a phase II study of BIBN 4096 to evaluate the safety and efficacy of a first in class non-peptide, parenteral CGRP-receptor antagonist.
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In order to identify risk factors for CNS ischemic complications at presentation and during follow-up, Nesher and associates reviewed the charts of 175 patients with giant cell arteritis diagnosed between 1980 and 2000 at 4 Jerusalem hospitals.
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Cardiac surgery may be complicated by ischemic stroke as well as more non-specific cognitive disturbances. Could prophylactic neuroprotective strategies be employed?
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The National Cholesterol Education Program, a product of a collaboration of the National Heart, Lung, and Blood Institutes, the American College of Cardiology, and the American Heart Association, has updated its clinical practice guideline on cholesterol management.
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Methylprednisolone significantly improves the recovery of peripheral vestibular function in patients with vestibular neuritis, whereas valacyclovir does not.
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Absence of evidence-based medicine is both humbling, as well as a reminder of how substantial a role the art and oral tradition of medicine plays in the care of neurologic patients.
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These studies provide additional data about the higher risk of relapse, and the greater potential for progression of disability following childbirth.
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It seems prudent to strongly consider use of melatonin in our cognitively delayed patients with disordered sleep, but to monitor those with epilepsy very closely for exacerbation, and withdraw the drug.