Articles Tagged With: Dementia
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Greater Weight Loss Later in Life Is Associated with Increased Risk of Mild Cognitive Impairment
In a population-based, prospective study of subjects 70 years of age or older, increasing weight loss per decade from midlife to late-life was associated with an increased risk of incident mild cognitive impairment.
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HIPAA Can Be Challenging with Dementia Patients
Patients with dementia may require special attention with regard to the Health Insurance Portability and Accountability Act, as they aren’t always able to communicate effectively or give permission for clinicians to talk to others about their healthcare.
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False Information from Your Patients with Dementia Threatens Their Safety
Growing concern about the patient safety risks posed by dementia is prompting some healthcare facilities to address the issue with policies and procedures designed to avoid misinformation and other threats.
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False Information from Patients With Dementia Threatens Safety
Growing concern about the patient safety risks posed by dementia is prompting some U.S. healthcare systems to address the issue with policies and procedures designed to avoid misinformation and other threats.
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Eating Behavior in Frontotemporal Dementias
In a prospective, controlled study of 49 patients with dementia and 25 healthy controls, marked hyperphagia is restricted to behavioral-variant frontotemporal dementia patients that is likely due to differing neural networks, while increased sucrose preference is likely controlled by a similar network in both behavioral-variant frontotemporal dementia and semantic dementia patients.
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Integrative Approaches to Alzheimer’s Disease
The medical community had warning. “Dementia in the Elderly: The Silent Epidemic,” a 1982 Annals of Internal Medicine landmark article, looked at the “greying of America” and noted one natural consequence of longer life span would be an explosive impact on the prevalence of dementia. Indeed, the epidemic has come — not only in the United States, but also globally, with dementia affecting an estimated 46 million people worldwide in 2015 and projected to affect 131 million by 2050.
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Postmortem Evidence of Limbic, Neocortical, and Basal Ganglia Deficits in Parkinson’s Disease Dementia
Postmortem brain tissue from 15 individuals with Parkinson’s disease dementia was analyzed by high-performance liquid chromatography and immunoassays, revealing widespread deficits in dopamine, serotonin, and noradrenaline innervation.
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Mediterranean Diet Increases Brain Volume
Higher adherence to the Mediterranean diet led to measurable increases in brain volume in a multi-ethnic sampling of older adults.
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Cerebrospinal Fluid Tau and Amyloid-ß1-42 in Patients with Dementia
In patients with clinically diagnosed dementia, the CSF biomarker profile of low CSF amyloid-ß1-42, high total tau, and high phosphorylated tau was seen in the majority of patients with clinically diagnosed Alzheimer’s disease. Substantial proportions of patients with non-Alzheimer’s dementia were also found to have the Alzheimer’s disease pathological profile. The value of CSF biomarker measurements in clinical practice is uncertain.
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Evaluating Dementia and Delirium in the Emergency Department
The term dementia is derived from the Latin word for “out of one’s mind.” It describes a deterioration of intellectual faculties, which may include memory, attention, learning, and judgment, and can be accompanied by emotional disturbance and personality changes. It is most often a result of a neurodegenerative process, such as Alzheimer’s disease, but also can be caused by more than 50 different diseases and disorders, including strokes, trauma, infectious diseases, and metabolic disorders.