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  • Intervention Reduces Distress of Surrogates

    Being a surrogate decisionmaker in the intensive care unit (ICU) can have long-term psychological consequences, including post-traumatic stress.

  • Timing of Ethics Consults Varies by Diagnosis, Language, and Ethnicity

    Farshid Dayyani, MD, PhD, joined the ethics committee at University of California Irvine (UCI) Medical Center in 2020. Then, the pandemic hit. Dayyani and colleagues wanted to know if patient characteristics (language, diagnosis, and race/ethnicity) affected the timing of ethics consult requests or the ethics team’s recommendations. There were limited data showing some racial and gender disparities in delays to obtaining ethics consults. The researchers saw the need for a more comprehensive analysis of ethics consults.

  • Are Ethics Committees Effective? Some Are Being Replaced with Alternative Model

    The vast majority of hospitals have ethics committees. Yet these committees vary in terms of their effectiveness, leading some ethicists to conclude it is time for a new approach.

  • Envenomations Update

    This article will give an overview of medically important non-marine envenomations in the United States, including their clinical manifestations, treatment, and disposition.

  • Identifying and Managing Rocky Mountain Spotted Fever

    Rocky Mountain spotted fever is an infectious disease that may be rapidly fatal if not rapidly recognized based on clinical findings and early institution of appropriate antibiotic therapy. The epidemiologic shift of this disease makes it important for all healthcare providers to be familiar with the current status, clinical presentation, and therapy for Rocky Mountain spotted fever.

  • Navigating Hypoglycemia in Diabetes Care: Clinical Management Strategies and Glucagon Treatment Options

    Hypoglycemia, defined as a blood glucose level less than 70 mg/dL, can be life-threatening, particularly with insulin therapy, and imposes a significant risk factor leading to severe morbidity and increased medical costs. As a preventable and potentially acute complication of diabetes management, providing proper patient education, identifying key risk factors, and tailoring treatment approaches are crucial for prevention.

  • Do We Need to Stop Renin-Angiotensin Inhibition Before Non-Cardiac Surgery?

    A randomized study of stopping vs. continuing renin-angiotensin system inhibitors prior to elective non-cardiac surgery in older patients did not decrease the incidence of myocardial injury and may have increased the incidence of hypertensive adverse events.

  • Are Beta-Blockers Post-MI Still Necessary?

    A large, multicenter, international, randomized clinical trial of long-term beta-blocker therapy vs. no such therapy in contemporary acute myocardial infarction patients who had coronary artery angiography-guided therapy and left ventricular ejection fractions ≥ 50% found no differences in the primary endpoint of all-cause mortality and recurrent myocardial infarction.

  • Is Weight Loss the Key to Heart Health?

    The second trial of semaglutide in obese patients with heart failure and preserved left ventricular ejection fraction, this one in people with type 2 diabetes, also has shown significant improvements in symptoms and exercise function with significantly fewer adverse effects than placebo-treated patients.

  • Transcatheter Myotomy for Left Ventricular Outflow Tract Obstruction

    Initial experience with a new transcutaneous transcatheter electrosurgery device using intramyocardial guidewires to create left ventricular upper septum myotomies to enlarge the outflow tract in symptomatic patients with hypertrophic cardiomyopathy, and potentially to enhance transcatheter left heart valve replacement when outflow tract obstruction compromises the procedure, is described in this report from a single center.