Articles Tagged With: antibiotic
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Discharge Antibiotic Prescriptions Often Are Inappropriate with Regard to Choice, Dose, Duration
Seventy percent of discharge antibiotic prescriptions are inappropriate.
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Ventilator-associated Pneumonia with Minimal Ventilatory Requirements — Discontinuing Antibiotics After Three Days
Discontinuation of empiric antibiotic therapy given for treatment of presumed ventilator-associated pneumonia can be discontinued safely after three days in patients with minimal ventilator requirements.
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Antibiotic Stewardship in Outpatient Settings
The implementation of antibiotic stewardship principles in all outpatient settings is crucial to the struggle against growing antimicrobial resistance and to optimal patient outcomes.
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FDA Is Approving New Antibiotics — But Is the Result Just Higher Prices for More of the Same?
Eight new antibiotics received FDA approval from 2010-2015.
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Reported Beta-lactam Allergy Is Associated with More Adverse Events Among Inpatients
A prospective cohort study from three hospitals determined that patients who did not receive a preferred beta-lactam antibiotic were at greater risk for an adverse event (adjusted odds ratio, 3.1; 95% confidence interval, 1.28-7.89) compared to controls without a beta-lactam allergy.
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Antibiotics, Breastfeeding, and the Intestinal Microbiota
Breastfeeding is associated with less frequent bacterial infections and with less subsequent obesity. Using antibiotics reduces or removes these favorable effects of breastfeeding, perhaps via alterations in the intestinal microbiota.
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Guideline Update: Adults with Hospital-acquired and Ventilator-associated Pneumonia
The most notable new recommendation of the updated hospital-acquired pneumonia/ventilator-associated pneumonia guideline may be its endorsement of limiting the duration of antibiotic therapy to seven days in most cases.
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Too Much of a Good Thing
In the United States in 2010 and 2011, an estimated 30% of outpatient oral antibiotic prescriptions may have been inappropriate, a finding that supports the need for establishing a goal for outpatient antibiotic stewardship.
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30% of Outpatient Antibiotics Unnecessary
We often hear of inappropriate antibiotic use, including the wrong drug for the bug, the wrong duration of therapy, and the failure to scale down from a broad spectrum drug once the etiology of an infection is determined. But what if you took almost a third of your drug formulary and hurled it out the window, where it will do nothing except help kill off susceptible bacteria in the environment and select out resistant strains?
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Prevent the Bug, Save the Drug:
Once largely consigned to separate silos, infection prevention and antibiotic stewardship are starting to show signs of a powerful partnership. The CDC’s most recent update on the threat of antibiotic-resistant bacteria emphasizes that drug stewardship and infection control must essentially be inseparable if they are going to be successful.