Articles Tagged With: circadian
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Neuropeptides in Patients with Restless Legs Syndrome
The diurnal onset of restless legs syndrome (RLS) has been replicated in a mouse model using central instillation of the main melanocortin agonist, α-MSH, which stimulates excessive locomotion and grooming in rodents as well as a state of hyperalgesia. The actions of β-endorphin (β-EDP) oppose those of α-MSH, since β-EDP promotes passivity and analgesia. In this study, these prohormones were measured in plasma and cerebrospinal fluid in patients with RLS and compared to controls. Patients with RLS had elevated levels of α-MSH and lower levels of β-EDP compared to the control group.
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Bright Light Therapy in Depression and Insomnia Associated With Parkinson’s
Bright light therapy (10,000 lux intensity for 30 minutes twice daily) and a low intensity control light showed similar efficacy in treatment of depression associated with Parkinson’s disease; the bright light therapy showed some advantages in improving subjective quality of sleep.
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Late Sunsets, Sleep Deprivation, and Adverse Outcomes
All living organisms have 24-hour circadian rhythms. A body of evidence is accumulating that chronic disruption of this important rhythm may result in poor health outcomes. These negative consequences of disrupted circadian rhythms might be prevented by modifying work and sleep schedules.
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Late Sunsets, Sleep Deprivation, and Adverse Outcomes
All living organisms have 24-hour circadian rhythms. A body of evidence is accumulating that chronic disruption of this important rhythm may result in poor health outcomes. These negative consequences of disrupted circadian rhythms might be prevented by modifying work and sleep schedules.