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Articles Tagged With: efficacy

  • Is There an Ideal Time to Administer Antihypertension Medications?

    Taking all antihypertensive agents before bed vs. upon awakening in hypertensive patients showed there was less hypertension during sleep and few cardiovascular events over a six-year follow-up.

  • New Contraceptive Patch Is a Weekly Option

    Twirla, a new low-dose contraceptive patch, is effective at preventing pregnancy among American women, according to researchers. Phase III clinical trial results were favorable for efficacy, safety, and tolerability of a levonorgestrel/ethinyl estradiol transdermal delivery system. The new patch uses a progestin and contains less estrogen than prior patches.

  • DSMBs Have Helped Advance Safe, Effective HIV/AIDS Research

    Data safety monitoring boards (DSMBs) have played a big role in helping the most effective and safe HIV therapies advance.

  • The Work of Vaccinating Frontline Healthcare Workers Against COVID-19 Begins

    Hospitals are scrambling to ensure a smooth and effective process for vaccinating frontline healthcare workers against COVID-19. Leaders need to quickly equip their personnel with enough information to persuade them that the vaccine is safe and effective.

  • A New Nonhormonal Vaginal Gel Contraceptive

    In this single-arm, open-label, Phase III study of a novel vaginal pH regulator gel among 1,384 sexually active women aged 18 to 35 years, the seven-cycle cumulative pregnancy rate was 13.7% (95% confidence interval, 10.0% to 17.5%).

  • High Efficacy of COVID-19 Vaccines Buoys Hopes

    Although questions and caveats remain, preliminary reports of two new COVID-19 vaccines in the 90% to 95% effectiveness range have bolstered hopes that healthcare workers may soon be protected and potentially large portions of the public immunized in 2021.

  • Healthcare Workers Await the First SARS-CoV-2 Vaccine

    With the first vaccine for SARS-CoV-2 on the horizon and targeted for healthcare workers, there are safety concerns and trust issues that threaten to undermine immunization. However, all new vaccines are followed closely for adverse effects, and the oversight of COVID-19 immunization will include multiple systems of passive and active surveillance.

  • COVID-19 Vaccine Update

    There are dozens of vaccine candidates undergoing investigation in human and animal trials. Only a few have reached Phase III testing. This is a closer look at those.

  • IqYmune for CIDP

    IqYmune is a highly purified 10% concentration of human immunoglobulin obtained from healthy volunteers. It appears to have similar efficacy in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) as conventional intravenous immunoglobulin, with 76% of the study patients showing a significant improvement in a standardized disability score.

  • Trust but Verify: IPs, Colleagues Await a SARS-CoV-2 Vaccine

    Although there is broad concern about the rapid pace and oversight of COVID-19 vaccine development, infection preventionists are ready to trust the time-honored protocols and process for safety and efficacy.