Articles Tagged With: perinatal
-
Retrospective Cohort Analysis of Perinatal Outcomes Following Bariatric Surgery
In a retrospective study of a racially and ethnically diverse cohort in 2012-2018, patients with a live birth after bariatric surgery had a lower risk of preeclampsia, gestational diabetes or impaired fasting glucose, and having a large-for-gestational-age infant — but a higher risk of having a small-for-gestational-age infant — relative to matched controls who did not have bariatric surgery before their live birth.
-
Effectiveness of an Online e-Health Program in Ameliorating Postpartum Depression
This study demonstrated that combined use of universal depression screening and MomMoodBooster2, a cognitive behavioral therapy-based e-health program, were effective tools for treating women with depression in the perinatal period.
-
Supplemental Oxygen Therapy for Category II Fetal Heart Rate Tracings
This study demonstrated a statistically significant change in the use of supplemental oxygen therapy in women with category II fetal heart rate tracings in the absence of maternal hypoxia pre- and post-intervention, with no significant change in maternal or perinatal outcomes.
-
Zuranolone Trial Shows Early Promise as an Oral Neuroactive Steroid for the Treatment of Postpartum Depression
Zuranolone was approved by the Food and Drug Administration for the treatment of postpartum depression (PPD) in March 2019. One potential factor identified in PPD etiology is the dramatic perinatal changes in circulating levels of allopregnanolone, a neuroactive steroid with gamma-aminobutyric acid type A (GABAA) receptor positive allosteric modulator properties. In brain regions associated with emotion and self-perception, neural network connectivity supported by GABAergic signaling is positively correlated with plasma allopregnanolone concentrations in individuals with PPD vs. healthy postpartum female individuals.
-
Disease Severity and Perinatal Outcomes of Pregnant Patients with COVID-19
In this observational cohort study of patients with singleton gestation and positive coronavirus test, patients with severe or critical disease were at risk for perinatal complications compared to those who were asymptomatic. Patients classified with mild or moderate disease were not shown to have an increased risk compared to asymptomatic positive patients.
-
HIV Management During Pregnancy
Human immunodeficiency virus (HIV) infection during pregnancy carries a significant burden to healthcare systems, and continues to be of significant public health concern.
-
Perinatal Mental Health During the COVID-19 Pandemic: The Role of the OB/GYN
The obstetrical effect of COVID-19 has received attention worldwide. However, data examining the psychological effect on women in the perinatal period still are emerging. Although there is little doubt that COVID-19 has increased depression and anxiety in many demographic groups, a small amount of existing literature begins to give us some insight into the incidence, risk factors, and protective factors for mental illness in perinatal women during the COVID-19 pandemic.