Articles Tagged With: pregnancy
-
SARS-CoV-2 Infection During Pregnancy and Increased Risk of Preeclampsia
A meta-analysis of 28 observational studies found that having SARS-CoV-2 infection during pregnancy was associated with a 58% increase in the adjusted odds of having preeclampsia compared to those without SARS-CoV-2 infection during pregnancy.
-
Pregnancy-Associated Stroke Is Increasing in Frequency
Stroke during pregnancy or the puerperium is a rare event but accounts for a considerable part of maternal morbidity and mortality. The incidence has been increasing in all countries, particularly in wealthy industrialized countries, where pregnancy is being delayed considerably and other cardiovascular risk factors have taken on greater importance.
-
COVID-19 Vaccination, Pregnancy, Lactation, and Fertility: What Should the OB/GYN Know?
With the increasing circulation of the Delta variant, it has become critically important for the OB/GYN to discuss COVID-19 vaccination with patients, and, specifically, to address concerns related to pregnancy, lactation, and fertility. This article reviews the most recent guidance from the American College of Obstetricians and Gynecologists, the Society of Maternal-Fetal Medicine, and the American Society for Reproductive Medicine on vaccination in reproductive-age individuals.
-
Vaginal Misoprostol vs. Prostaglandin E2 Pessary for Induction of Labor at Term
In this randomized, noninferiority, clinical trial of pregnant women who underwent induction of labor with misoprostol compared to dinoprostone, the rate of vaginal delivery within 24 hours was higher in the misoprostol group. Maternal satisfaction, assessed by a visual analog scale, also was higher. Although the noninferiority of dinoprostone to misoprostol could not be demonstrated, the clinical risk-to-benefit ratio justifies the use of both drugs.
-
Is Black Race Associated with Major Depression Following Early Pregnancy Loss?
Reporting symptoms of having major depression one month after treatment for early pregnancy loss was about twice as common among Black women compared to non-Black women.
-
Mifepristone as an Adjunct to Misoprostol for Pregnancy Termination
In this prospective, double-blind, randomized, placebo-controlled trial, pretreatment with 200 mg of mifepristone 24 to 48 hours before labor induction using misoprostol significantly reduced time to delivery among demised fetuses between 14 and 28 weeks of gestation. Maternal complications were equivalent in both groups.
-
Researchers Study COVID-19 Vaccine Outreach to Pregnant Women
The results of a recent study highlight the gaps in COVID-19 vaccination among pregnant women in the United States. Although pregnant women are at increased risk for severe illness and death from the disease, many remain unvaccinated. -
The Association Between SSRIs and Congenital Anomalies
In this synthesis involving 15 meta-analytic studies, four studies demonstrated an association between paroxetine use during pregnancy and increased risk of major congenital anomalies (relative risk [RR], 1.18 [95% confidence interval (CI), 1.05, 1.32] to 1.29 [95% CI, 1.11-1.49]). For all selective serotonin reuptake inhibitors (SSRIs), the RR for major anomalies (1.10 [95% CI, 1.03, 1.16] to 1.27 [95% CI, 1.09, 1.47]) and cardiac defects (1.06 [95% CI, 0.94, 1.18] to 1.36 [95% CI, 0.61, 3.04]) were increased. This meta-analysis suggests an increased risk of cardiac and major anomalies with SSRI use, but the results should be interpreted with caution, since all included studies were meta-analyses of retrospective cohort studies.
-
Update on Adult Vaccinations in the ED with a Focus on SARS-CoV-2/COVID-19
Emergency departments have a unique role in public health. They care for a disproportionate number of patients who lack access to care in other venues. Emergency departments also can play a role in decreasing vaccine hesitancy, providing information to patients on the vaccine, answering their questions, and correcting misinformation when it is present. -
Does Maternal BMI Influence the Success of Trial of Labor After Cesarean?
In this retrospective cohort study between May 2007 and April 2016, women undergoing a trial of labor after cesarean (TOLAC) were analyzed to determine if pre-pregnancy or delivery obesity status made an impact on TOLAC success. Overall, maternal body mass index did not have a significant effect on TOLAC success rates.