Articles Tagged With: pregnant
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Overcoming COVID-19 Vaccine Hesitancy in Healthcare Workers
A striking 20% of nurses in the United States are refusing offers to be immunized with COVID-19 vaccine, according to the results of a national survey.
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Understanding the Utility of Hemoglobin A1c in Diagnosing Gestational Diabetes in Early Pregnancy
In this retrospective cohort study of 243 pregnant women who had combined hemoglobin A1c (HbA1c) and a two-step oral glucose tolerance testing at less than 21 weeks of gestation, median values of HbA1c were higher in women with gestational diabetes compared to nondiabetics (5.8% compared to 5.3%; P < 0.001). The predictive probability of using HbA1c in diagnosing diabetes in early pregnancy was high compared to two-step testing (area under the curve, 0.8), with an optimal diagnostic threshold of 5.6%. Although a HbA1c level of > 6.5% is diagnostic of early gestational diabetes, a lower diagnostic threshold might be justified during pregnancy.
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Outcomes in Pregnant Women Treated with Anti-Tumor Necrosis Factor-Alpha Biologic Therapy
In this population-based cohort study of 1,027 infants born to women treated with anti-TNF-α biologic therapy, there was an increased prevalence of preterm birth (adjusted odds ratio [aOR], 1.61; 95% confidence interval [CI], 1.29-2.02), cesarean delivery (aOR, 1.57; 95% CI, 1.35-1.82), and small for gestational age neonates (aOR, 1.36; 95% CI, 0.96-1.92) when treatment with anti-TNF was compared to non-biologic systemic treatment. Since disease processes varied greatly in these pregnant women, it was difficult to rule out confounding by disease severity (confounding by indication).
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.
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Many Serious Cardiac Complications of Pregnancy Are Preventable
Investigators determined about half of serious cardiac complications of pregnancy are preventable.
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The Risk of COVID-19 to Pregnant Healthcare Personnel
Are there recommended work restrictions for pregnant healthcare personnel during the COVID-19 pandemic? The Centers for Disease Control and Prevention is somewhat equivocal on the issue, essentially saying no heightened risk has been clearly established, but the known risk from similar viruses and influenza warrants caution.
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Malaria Prophylaxis During Pregnancy
In a retrospective study of American military women involving 50 treated with atovaquone-proguanil and 156 exposed to mefloquine, no increase in risk of fetal loss or adverse infant outcomes was identified. Atovaquone-proguanil seems safe for use in pregnancy, but data are limited.
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Trauma in Pregnancy: A Comprehensive Overview
The authors provide a concise, comprehensive overview of the unique anatomic and physiologic features of pregnancy, as well as modifications and considerations important for the management of the pregnant trauma patient.
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Infectious Disease Alert Updates
Lyme Carditis: Any AV Block of Concern; Syphilis Screening in Pregnancy a Must; Deferring INH Until Postpartum in HIV-Positive Women
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Lettuce for Sleep? Maybe, but Not in Salad Form
The authors of this single-blind randomized study found that 1,000 mg of culinary lettuce seed nightly for two weeks can improve sleep in pregnant women with insomnia.