Articles Tagged With: treatment
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Treatment of Progressive Multifocal Leukoencephalopathy
Progressive multifocal leukoencephalopathy, a rare opportunistic viral infection that occurs in patients who have chronic immunosuppression, has defied all attempts at treatment. This observational study, which pooled patient data from multiple centers around the world, showed that there is some benefit using checkpoint inhibitors to help reconstitute the immune system of these patients. However, survival, at best, is 50% of those treated.
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Long-Term Neurological Outcomes of Patients Treated with CAR-T Therapy
Chimeric antigen receptor (CAR)-T cell therapy is approved for the treatment of lymphoma, leukemia, and multiple myeloma, but its use is associated with early neurotoxicity in almost half of patients. Despite the incidence of neurotoxicity, long-term follow-up of patients after CAR-T infusion suggests that patients’ neurological examination, neuro-imaging studies, and cognition remain unaffected by this treatment.
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Informed Consent Requirements May Hinder Innovation in Stroke Treatments
IRBs and regulatory bodies should consider the changing scope of acute stroke care, and collaborate with investigators to design studies that can ethically answer important questions and allow innovation and progress in the field.
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Treatment of Acute Vertigo
Treating acute vertigo with an antihistamine was more effective than benzodiazepines for acute symptoms. However, there was no difference between the two medications in terms of resolution within one week or one month.
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Infectious Disease Alert Updates
Remaining Questions in Syphilis Treatment; The Great Imitator Imitates Again
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Remain Vigilant for Signs of Monkeypox
Emergency clinicians should include the possibility of monkeypox in any patient presenting with early symptoms suggestive of the illness and certainly for those with a new rash and epidemiological risk factors.
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Updated Abdominal Pain Guidelines Close Knowledge Gap
Without clear guidelines, patients could undergo unnecessary testing (or not receive tests they need), which could lead to misdiagnoses — or worse.
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Answering Patient Questions About COVID-19
Wright State University Boonshoft School of Medicine formed an educational task force to educate clinicians and answer community members’ questions about all things COVID-19. Easily referenced resources on COVID-19 are essential for healthcare professionals in speaking with patients. Easy-to-navigate, dependable, up-to-date sources of information help serve patients requiring specific and timely answers to questions. Having a “go-to” list of resources can reduce confusion about COVID-19, making vaccination updates and other conversations more productive.
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COVID-19 and Headache
Headache is a common feature of acute COVID-19 infection, as well as a long-standing feature of “long COVID” after recovery from the acute infection. Treatment is symptomatic, based on the characteristics of the headache syndrome.
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Noradrenergic Drugs for the Symptomatic Treatment of Alzheimer’s Disease
This meta-analysis provides evidence that drugs modulating the noradrenergic system could be effective in treating cognitive symptoms and apathy in patients with Alzheimer’s disease.