Critical Care Alert – January 1, 2024
January 1, 2024
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There was no significant difference in the incidence of acute kidney injury in patients given piperacillin-tazobactam vs. cefepime for sepsis.
In this secondary analysis of the BOUGIE trial, patient and operator characteristics may affect successful intubation with either technique despite no difference in outcomes in the primary analysis.
A short course of inhaled amikacin at therapeutic doses prevented the occurrence of ventilator-associated pneumonia without changes to duration of mechanical ventilation, length of stay, or mortality.
After extensive sensitivity analyses to account for severity of illness and confounding, a comparison of patient characteristics of those receiving extracorporeal membrane oxygenation (ECMO) to those treated with mechanical ventilation alone revealed that female patients, those with Medicaid, and those living in the lowest-income neighborhoods were less likely to be treated with ECMO.