Infectious Disease Alert – December 1, 2022
December 1, 2022
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2022-2023: A Severe Season for Respiratory Syncytial Virus
The 2022-2023 northern hemisphere respiratory syncytial virus (RSV) season began with fury, crowding hospitals and making many young children extremely ill. Meanwhile, advancing research points to potential means of better preventing RSV infection.
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Limiting Testing in Febrile Young Infants with Abnormal Urinalyses
According to a 26-site study, febrile infants younger than 2 months of age who have abnormal urinalyses are at very low risk of having meningitis and might not necessarily need to be subjected to lumbar puncture.
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Multi-State Tuberculosis Outbreak Due to Transmission from an Infected Bone Graft Product
An 80-year-old man with undiagnosed tuberculosis (TB) became a bone tissue donor after his death from a cardiac arrest. Bone graft product was given to 113 recipients in 20 states, of whom three died of TB. All living recipients were started on treatment for TB at a median of 69 days after bone product implementation.
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Severe Monkeypox
The Centers for Disease Control and Prevention has summarized 57 cases of individuals hospitalized with severe monkeypox, most of whom were immunocompromised men and a number of whom had delayed initiation of antiviral therapy.
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Disseminated Infection Due to Neisseria gonorrhoeae
Only 0.24% of patients with gonorrhea had disseminated infection, with septic arthritis occurring in approximately one-half.
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Genital Herpes — No Longer Just HSV-2 as HSV-1 Makes its Move
Viral shedding after a first episode of genital herpes simplex virus type 1, which is gradually replacing herpes simplex virus type 2 as the major cause of genital infection, occurred in 12.1% at weeks 8-12 and decreased to 7.1% at the end of one year.
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Infectious Disease Alert Updates
Animal Reservoirs for Human Infection; Novel Rat-Derived HEV Infection in Humans; Household Contamination with Monkeypox