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AMA Masthead 1

Integrative Medicine Alert – February 1, 2024

February 1, 2024

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  • Racing Against Depression and Anxiety: Measuring Running vs. Antidepressant Therapy

    This prospective study blending randomization with preference compared a running program with antidepressant therapy in adults with depression or anxiety and showed an improvement in mental health in both arms. However, physical health parameters increased only in the running group.

  • Sleeping Away Dementia

    In this long-term observational study of sleep efficiency in the Framingham Heart Study population, researchers found a strong correlation between a decline in duration of slow-wave sleep during aging and the risk of incident dementia from all causes. However, a direct cause-and-effect relationship cannot be determined from this observational study.

  • Examining Microbiome Metabolites and Parkinson’s Disease

    A Mendelian randomization study shows that trimethylamine N-oxide (TMAO) and its precursor metabolites are not associated with risk of Parkinson’s disease (PD) but have both positive and negative causal effects on some indicators of PD severity and progression.