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Internal Medicine Alert – May 15, 2024

May 15, 2024

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  • Fat May Be the Healthiest Part of Dairy

    There are numerous health benefits of dairy fat intake and dairy fat lacks the problems associated with dairy sugar and proteins.

  • Meningococcal Disease Is on the Rise

    The number of cases of infection with Neisseria meningitidis is increasing in the United States. The majority of presentations are with bacteremia; meningitis is infrequent.

  • Better Outcomes for Acute Stroke Patients Who Arrive Rapidly at Endovascular-Capable Centers

    The SELECT2 trial was structured to identify which patients with large ischemic strokes would benefit from endovascular thrombectomy and analyzed the effect of direct arrival at a thrombectomy-capable center compared to transfer from a primary stroke center.

  • Timing of Biomarker Changes in Alzheimer’s Disease

    In a longitudinal multicenter, nested case-control study of cognitive normal participants from China, the time courses of key Alzheimer’s disease biomarkers were identified during the 20 years preceding clinical diagnosis of sporadic Alzheimer’s disease.

  • Comparing Early vs. Late-Onset MS

    A recent retrospective study, combining data from a United Kingdom patient registry with a United Kingdom neuropathology tissue bank, showed that late-onset multiple sclerosis (MS), referring to disease onset after age 50 years, is linked with increased disability and quicker progression compared to MS onset at a younger age, and has distinct pathological features.

  • Cefepime and Enmetazobactam Injection (Exblifep)

    The U.S. Food and Drug Administration has approved the combination of cefepime and enmetazobactam (FPE) for the treatment of complicated urinary tract infections. Cefepime-enmetazobactam was granted a priority review and a five-year marketing exclusivity as part of the Generating Antibiotic Incentive Now (GAIN) Act incentivizing development of new anti-infectives. FPE is distributed by Allecra Therapeutics SAS as Exblifep.

  • Which Is the Key Lead?

    The patient whose ECG appears in the figure is a middle-aged man who presented to the emergency department with new chest pain. Should the cath lab be activated?