OB/GYN Clinical Alert – June 1, 2023
June 1, 2023
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Azithromycin Prophylaxis for the Prevention of Maternal Sepsis or Death in Women Undergoing Vaginal Delivery
A single oral dose of azithromycin dramatically reduced the risk of maternal sepsis or death among women planning vaginal deliveries compared to placebo but had little effect on neonatal sepsis or mortality.
Menstrual Suppression Method Outcomes Among Transgender and Gender-Diverse Adolescents
In a retrospective chart review of transgender and gender-diverse adolescents at a single institution seeking menstrual suppression methods, most individuals had high rates of method continuation, amenorrhea, improved bleeding, and a reduction in dysphoria and mood symptoms.
Surgical Management of Missed and Incomplete Abortion: Is Hysteroscopy Useful?
In this randomized controlled trial of 563 women comparing vacuum aspiration and operative hysteroscopy for incomplete spontaneous abortion, there was no difference in pregnancy rates within the following two years (62.8% hysteroscopy vs. 67.6% vacuum aspiration; risk difference, -4.8%; 95% confidence interval, -13% to 3%).
Identifying and Testing BRCA Gene Variant Carriers Meeting NCCN Criteria
A large percentage of patients who meet criteria for breast cancer gene (BRCA) testing based on family history do not have it completed until after a personal cancer diagnosis, thus missing the opportunity for risk-reducing strategies.