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    Home » Newsletters » Internal Medicine Alert

    Internal Medicine Alert

    www.reliasmedia.com

    November 15, 2020

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    As a valued subscriber to the wealth of resources published by Relias Media, we are sending this reminder that your new issue is now available online. The article in this issue is listed below:

    Antibiotic Use in COVID-19 Patients

    Fifty-seven percent of patients with COVID-19 infection treated at 38 hospitals in Michigan received early empiric antibiotics, although researchers documented community-onset bacterial coinfection in only 3.5%.

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    Oral Calcitonin Gene-Related Peptide Antagonist for Migraine Prevention

    Atogepant, an oral calcitonin gene-related peptide antagonist, was shown to be effective and safe for migraine prevention.

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    Auditory Startle Response as a Predictor of Recovery from Coma

    Preserved habituation of the auditory startle response, performed bedside, indicates intact cortical structures and cortico-cortical white matter tract connections. Preservation of this reaction in patients with unresponsive wakefulness can help distinguish the vegetative state from minimally conscious state and may even predict eventual awakening.

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    Gut Microbiome in Patients at Risk for Parkinson’s Disease

    Certain risk factors and prodromal markers of Parkinson’s disease (PD), such as constipation and rapid eye movement sleep behavior disorder, are associated with specific bacterial compositions of the gut. However, the value of gut microbiome data to predict the risk of PD development needs further investigation.

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    COVID-19 Vaccine Update

    There are dozens of vaccine candidates undergoing investigation in human and animal trials. Only a few have reached Phase III testing. This is a closer look at those.

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    Is There Right Ventricular Strain or Acute Pulmonary Embolism?

    The ECG in the figure was obtained from a middle-age woman who presented with new dyspnea. Is the T wave inversion in the inferior leads a reflection of right ventricular “strain” from acute pulmonary embolism? If not, what else might cause these ECG findings?

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    www.reliasmedia.com

    Internal Medicine Alert

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    Internal Medicine Alert (Vol. 42, No. 21) - November 15, 2020
    November 15, 2020

    Table Of Contents

    Antibiotic Use in COVID-19 Patients

    Oral Calcitonin Gene-Related Peptide Antagonist for Migraine Prevention

    Auditory Startle Response as a Predictor of Recovery from Coma

    Gut Microbiome in Patients at Risk for Parkinson’s Disease

    COVID-19 Vaccine Update

    Is There Right Ventricular Strain or Acute Pulmonary Embolism?

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    Financial Disclosure: Internal Medicine Alert’s Physician Editor Stephen Brunton, MD, is a retained consultant for Abbott Diabetes, Acadia, AstraZeneca, and Boehringer Ingelheim; and he serves on the speakers bureau of AstraZeneca, Boehringer Ingelheim, Janssen, Lilly, and Novo Nordisk. Peer Reviewer Gerald Roberts, MD; Editor Jonathan Springston; Editor Jason Schneider; Editorial Group Manager Leslie Coplin; and Accreditations Director Amy M. Johnson, MSN, RN, CPN, report no financial relationships relevant to this field of study.

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