Neurology Alert – March 1, 2003
March 1, 2003
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Another Drug for the Migraine Prophylaxis Armamentarium
Several lines of evidence suggest that ace inhibition and/or angiotensin receptor blockade can be effective for migraine prevention. Lisinopril has already been shown to reduce migraine headache. -
A New Benign Sexual Headache: Sildenafil (Viagra®)-Induced Migraine
According to the pdr,1 16% of patients using sildenafil in clinical trials reported headache compared with only 4% of controls. Kruuse and associates studied the effect of sildenafil use apart from sexual activity in 12 patients with a history of migraine without an aura. -
Rasagiline in Early Parkinson’s Disease
Like its cousin selegiline, rasagiline is a selective irreversible inhibitor of monoamine oxidase type B. Rasagiline has been shown to improve the motor and cognitive signs of experimental parkinsonism, and preliminary studies have demonstrated that the compound is more potent than selegiline. -
New Practice Parameters for Treatment of Seizures
Practice parameters from the aan are strategies for patient management that assist physicians in clinical decision-making. These recommendations are derived from a thorough review that not only summarizes the available evidence-based medicine but, more importantly, assesses the quality of the data being reviewed. -
A Look at Some Memorable Brains
Disorders of memory are frequently studied, but exceptional recall abilities have been the subject of relatively few investigations. In an effort to understand the neural basis of superior recall, -
Demyelinating Neuropathy and Antineurofilament Antibodies
Among patients with plasma cell dyscrasias and polyneuropathy, most have monoclonal gammopathy of undetermined significance (MGUS), of which 50% are IgM in type. Most of these demonstrate activity against myelin-associated glycoprotein (MAG). -
A Fishy Story About Stroke
Several previous studies have reported inverse associations between fish intake and the risk of stroke in men and women. A randomized trial in patients with coronary heart disease, however, found that supplementation with fish oil reduced the risk of acute myocardial infarction but not of stroke. -
Muscle-Nerve Root Correlation for EMG
Retrospective review of needle emg findings on 45 patients studied during a 20-year period, with surgically verified compression of a single lumbosacral nerve root, was undertaken to determine the accuracy of traditional myotomal charts used to localize nerve root involvement. -
Pharmacology Watch: Smallpox Vaccination Guidelines Published by CDC
The Centers for Disease Control and Prevention published Smallpox Vaccination and Adverse ReactionsGuidance for Clinicians in the Jan. 24th edition of Morbidity and Mortality Weekly Report. The guidance is a thorough review of the smallpox vaccine with a well-illustrated compendium of complications.