Neurology Alert – July 1, 2021
July 1, 2021
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A population-based, prospective cohort study of women in the United Kingdom found no association between the number of lumbar segments with radiographic pathology and severity of back pain-related disability.
The majority of patients with moderate to severe traumatic brain injury who survive and are treated in acute rehabilitation centers will recover consciousness.
CSF Biomarkers May Distinguish MSA from Lewy-Body Alpha-Synucleinopathies Before the Onset of Debilitating Symptoms
In patients with autonomic failure, the combination of elevated neurofilament light and alpha-synuclein oligomers in the cerebrospinal fluid can distinguish between multiple system atrophy and Parkinson’s disease/dementia with Lewy bodies. Early diagnosis is critical for the development of treatment trials.
Graft-versus-host disease is common in allogeneic bone marrow recipients, but neuromuscular complications are unusual (8%). The most common neuromuscular complication is an immune-mediated myositis that responds to treatment with immunosuppressive therapies.
This study evaluated the use of dietary conjugated linoleic acid (CLA) supplementation to modulate the disease outcome in a spontaneous mouse model of central nervous system autoimmunity and also studied patients with relapsing-remitting multiple sclerosis receiving CLA supplementation. CLA may act as a modulator of the gut-brain axis by targeting immune cells in the gut, with a subsequent effect in the brain.