OB/GYN Clinical Alert – April 1, 2020
April 1, 2020
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Early Loss of Ovarian Function May Increase Risk for Cardiovascular Disease
Natural and surgical menopause appear to be associated with an increased risk for cardiovascular disease.
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Can We Liberalize Intrauterine Device Insertion Protocols?
In this retrospective cohort study, the rate of luteal phase pregnancy was 0.4% among 239 women who did not meet pregnancy checklist criteria for intrauterine device insertion.
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Vaginal Dryness: The Keystone Symptom of Postmenopausal Sexual Dysfunction?
In a large, cross-sectional, multicenter study in Italy that evaluated factors predictive of sexual dysfunction, vaginal dryness correlated independently and negatively with each Female Sexual Function Index domain.
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17P to Prevent Recurrent PTB in Singleton Gestations: The PROLONG Study
In this large, double-blind, placebo-controlled, international trial, pregnant women at risk for preterm birth (PTB) between 16-36 weeks gestational age were randomized to an intramuscular weekly injection of either 17-hydroxyprogesterone caproate (17P) or placebo. There was no difference in rates of PTB or neonatal morbidity between these two groups. In comparison to the Meis trial published in 2003, the findings of the PROLONG trial question the use of intramuscular 17P injection as the cornerstone of PTB prevention.