Clinical Cardiology Alert – July 1, 2016
July 1, 2016
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An evaluation of the predictive accuracy of the new pooled Cohort Risk Equation in > 300,000 subjects without heart disease or diabetes and a low-density lipoprotein cholesterol level between 70-189 mg/dL followed for five years showed that the new equation markedly overestimated the observed risk of cardiovascular events.
Asymptomatic patients suffering from moderate aortic stenosis and regurgitation with preserved left ventricular function have the same prognosis as asymptomatic patients with severe aortic stenosis and normal left ventricular function and should be followed closely for the development of symptoms.
Data from transcatheter aortic valve replacement procedures performed at German hospitals without on-site cardiac surgery shows relatively low rates of major complications and mortality similar to hospitals with full surgical programs.
In a recent analysis, abnormalities of von Willebrand factor were much more common in dysfunctional prostheses and were associated with gastrointestinal bleeding and angiodysplasia.