Clinical Cardiology Alert – January 1, 2020
January 1, 2020
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CABG vs. PCI for Left Main Disease at 5 Years
Five years after randomizing 1,905 patients with left main disease to coronary artery bypass grafting or percutaneous coronary intervention, researchers found no significant difference in the primary composite outcome of death, stroke, or myocardial infarction.
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Is the Physical Exam an Anachronism in Heart Failure?
In the PARADIGM-HF trial, signs of congestion during physical exam were related to outcomes and the improved outcomes observed with valsartan/sacubitril vs. enalapril.
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CRT Nonresponders Experience Poor Outcomes, Warrant More Aggressive Management
The ADVANCE CRT registry revealed a significant minority of patients fail to respond to cardiac resynchronization therapy, conferring a worse prognosis.
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Perioperative Management of Direct Oral Anticoagulants
A simple protocol for managing atrial fibrillation patients on direct oral anticoagulants perioperatively was shown to produce low levels of major bleeding and thromboembolism for 30 days postoperatively.
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Predicting the Progression of Chronic Aortic Regurgitation
A large database observational study of patients with chronic aortic mild or moderate regurgitation (AR) largely due to bicuspid aortic valve or aortic root dilatation showed that it was largely an indolent disease, with only 20% progressing to moderately severe AR in five years.