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Heparin-induced thrombocytopenia is an iatrogenic, potentially life-threatening complication that occurs after exposure to heparin therapy in hospitalized patients. Early recognition and timely initiation of treatment are critical for improved prognosis.
Adult patients experiencing sepsis with hypotension but who did not meet the definition of septic shock received a median of 800 mL of intravenous fluid prior to initiation of norepinephrine 0.05 mcg/kg/min as a non-titratable infusion. Patients in this early vasopressor group had much lower odds of failing to achieve their primary outcome of adequate mean arterial pressure and tissue perfusion when early norepinephrine was provided.
There are several distinct trajectories of recovery after acute respiratory failure. The group with the highest physical function consisted primarily of younger women who experienced less continuous sedation time and shorter ICU length of stay.
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Financial Disclosure: Critical Care Alert’s Physician Editor Betty Tran, MD, MSc, Nurse Planner Jane Guttendorf, DNP, RN, CRNP, ACNP-BC, CCRN, Peer Reviewer William Thompson, MD, Executive Editor Shelly Morrow Mark, Accreditations Manager Amy M. Johnson, MSN, RN, CPN, and Editorial Group Manager Leslie Coplin report no financial relationships relevant to this field of study.
