Cardiology Topics
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Is It Better to Up-Titrate Medications Faster in Acute Heart Failure Patients?
Early intensive up-titration of guideline-recommended therapy in patients admitted for heart failure reduced 180-day readmission and all-cause mortality at the cost of more adverse events (but not serious or fatal ones).
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Is Screening for Atrial Fibrillation Cost Effective?
Self-screening for atrial fibrillation in elderly individuals could lead to lower stroke rates, prevent bleeding-related hospitalizations, and save money.
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New Therapy for Resistant Hypertension
Aprocitentan demonstrated efficacy for additional therapy beyond standard multidrug treatment in resistant hypertension.
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Just How Good is ‘Good’ Cholesterol?
Investigators challenge high-density lipoprotein levels as the standard for predicting cardiovascular disease risk.
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Persistent Asthma Patients Show More Plaque Buildup, Inflammation
Pulmonary ailment could speed carotid artery damage, create more inflammatory biomarkers.
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Importance of Medication Adherence in Ischemic Heart Disease
The results of a subanalysis of the ISCHEMIA trial indicated about one-quarter of patients in both conservative and invasive strategy groups were nonadherent to recommended medical therapy at baseline. Nonadherence was associated with worse health status in both groups at baseline and after one year.
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Are Renal Artery Denervation Efficacy Claims Too Good to Be True?
Three-year follow-up data from the SYMPLICITY HTN-3 trial of renal denervation provide support for long-term safety of this technique and suggest blood pressure benefit.
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The Right Dose at the Right Time: Improving Hypertension Outcomes
An online study of evening vs. morning administration of patients’ usual antihypertensive medications, with a median five-year follow-up, revealed there is no difference in major cardiovascular outcomes between the two periods.
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Another Marker of Severe Mitral Regurgitation
A small retrospective study showed Doppler echocardiography-derived left ventricular ejection time is an independent predictor of adverse outcomes in patients with moderate or worse mitral valve regurgitation.
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Is Illicit Substance Use Associated with Atrial Fibrillation?
An observational study of a huge cohort of patients admitted to California hospitals showed patients who used cocaine, methamphetamine, opiates, and cannabis were at a higher risk of developing atrial fibrillation vs. those with similar risk factors who did not use the substances.