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The randomized evaluation of long-term anticoagulation Therapy (RE-LY) trial was a study that compared two doses of a new direct-thrombin inhibitor, dabigatran, to warfarin for stroke prevention in patients with atrial fibrillation.
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Mineralocorticoid receptor blockers have demonstrated improved survival in class III-IV heart-failure patients (spironolactone) and post-acute myocardial infarction patients with systolic dysfunction heart failure (eplerenone).
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This paper reports results from the resynchronization-Defibrillation for Ambulatory Heart Failure Trial (RAFT). This was a multicenter, double-blind, randomized trial testing the hypothesis that addition of resynchronization therapy (CRT) to an ICD, compared to an ICD only in patients with New York Heart Association (NYHA) class II or class III symptoms, left ventricular systolic dysfunction, and a widened QRS complex would improve survival and reduce hospitalizations.
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This paper analyzes data from the national icd registry, which tracks ICD implantations for the primary prevention of sudden death in the United States.
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The efficacy of statins in preventing cardiovascular events is well known, but approximately 10% of patients will develop elevations in liver function tests (LFTs).
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Patients taking dual anti-platelet therapy (DAPT) with aspirin and clopidogrel are at higher risk of bleeding with coronary artery bypass graft surgery (CABG) than those taking aspirin alone.
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Statins and liver function; dosing timing for thyroxine; rivaroxaban for VTE, DVT, and stroke; echinacea and the common cold; and FDA actions.
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This paper describes the results of a study which compared two energy types, cryoenergy and radiofrequency (RF), for catheter ablation in patients with atrioventricular nodal reentrant tachycardia (AVNRT).
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Rivaroxaban may be dabigatran's first competitor; a new way to measure non-adherence to medication therapy; FDA Actions.
