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It remains debatable as to whether individuals who present with a non-ST-segment elevation MI (NSTEMI) or acute coronary syndrome (ACS) should be managed with a selective or elective invasive strategy vs an approach performing angiography in all patients.
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Anticoagulation with vitamin k antagonists is the standard recommendation for patients with nonvalvular atrial fibrillation and risk factors for stroke. The benefits of warfarin in such patients have been well shown in many clinical trials. Therapy with warfarin, however, is often complicated by the dietary and drug interactions, so that even with frequent monitoring, precise control of the anticoagulation level is difficult.
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The differentiation of constrictive pericarditis from restrictive cardiomyopathy can be difficult, but the treatment implications are great.
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Patients with a positive CT scan for coronary calcium often have a stress test. Askew and colleagues from the Mayo Clinic asked whether such patients should undergo repeat stress testing if the first one is negative or low risk?
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This remarkable study is a population analysis of a huge cohort of children in Denmark who were followed, since 1930 or later, for the presence of coronary heart disease (CHD), and had all mandatory annual examinations at schools in Copenhagen.
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This paper gives the results of the substrate Mapping and Ablation in Sinus Rhythm to Halt Ventricular Tachycardia (SMASH-VT) study. This study was designed to test the hypothesis that early prophylactic catheter ablation in patients with implantable cardioverter defibrillators (ICD) would decrease the frequency of ICD shocks during follow-up.
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Rosiglitazone (Avandia) implicated in yet another study; Prilosec and Nexium not associated with cardiac events; Anastrozole (Arimidex) shown more effective than tamoxifen for treatment of early-stage breast cancer; antibiotics show no effect on sinusitis; FDA actions.
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Patent Foramen Ovale (PFO) has been associated with cryptogenic stroke in young individuals, but the association is less clear in older individuals where other causes of stroke predominate.
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