Clinical Publication
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Children Undergoing Stem Cell Transplant Lack Palliative Care
Palliative care teams can shorten length of stay, prevent readmissions, improve patient satisfaction, lower costs, and reduce burnout rates.
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Clinicians, Researchers Need New Framework for Ethical Management of Sickle Cell Disease
A new tool characterizes sickle cell disease pain as its own distinct problem, deserving of appropriate treatment. The tool suggests healthcare providers use the patient’s subjective report of their pain experience as data for informing treatment recommendations.
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IRBs Determine Acceptable Risk for Pediatric Studies
IRBs may be disinclined to approve study protocols based on the mistaken belief there is little public support for net-risk pediatric research. Thus, researchers should show IRBs data on the risks of the interventions in question. To demonstrate the study’s social value, researchers could explain how the approach under investigation could help address an important health condition.
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Researchers Encounter Challenges with Study Development Protocols
Tutorial videos and webinars, in-person training, and sample forms are some of the ways researchers try to keep up with IRB protocols to prevent any study delays.
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Unique Ethical Issues with Research on Difficult-to-Treat Depression
Researchers should focus on these three areas: How to define this group of patients, which is heterogenous; how to acquire and interpret clinically meaningful outcome metrics; and how to design clinical trials to promote generalizability.
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Are Neurotechnology Tools Designed Ethically? Public Is Skeptical
Industry members cannot just assume people trust them to design devices ethically. Marketing campaigns and advertisements are one way to spread the message. But even more fundamental is incorporating patient and end user feedback in the design process.
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Citizen Science Projects Surging, But Often Lack IRB Ethical Oversight
Failure to return results, exploitation of participants, poor quality data, and power imbalance are top ethical worries. Citizen scientists should pay attention to issues of power and exploitation, and think about what processes to use to stay ahead of those concerns.
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Clindamycin Vaginal Gel 2% (Xaciato)
Clindamycin gel can be prescribed to treat bacterial vaginosis in women age 12 years and older.
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Screen Older Heart Failure Patients for Transthyretin Cardiac Amyloidosis
A screening study of heart failure patients ≥ age 60 years, left ventricular ejection fraction ≥ 40%, and left ventricle wall thickness ≥ 12 mm revealed 6.3% prevalence of transthyretin cardiac amyloidosis, a highly treatable disease.
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Is Physical Activity Associated with Mortality Risk in Parkinson’s Disease?
In individuals with Parkinson’s disease (PD), physical activity (PA) at all intensities was associated with lower all-cause mortality rates, with the greatest reduction seen in individuals who maintained PA before and after PD diagnosis.