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  • Indacaterol Inhalation Powder (Arcapta™ Neohaler)

    An ultra long-acting, orally-inhaled beta2-adrenergic agonist (LABA) has been approved for the treatment of chronic obstructive pulmonary disease (COPD). Indacaterol is formulated as a dry powder and is the first beta2-agonist to be dosed once-daily. It is marketed by Novartis as Arcapta™.
  • A WCT with 'P' Waves?

    Interpret the 12-lead ECG shown above obtained from a hemodynamically stable patient with underlying heart disease and new-onset palpitations. Despite the apparent QRS widening is this sinus tachycardia (arrow pointing to 'P waves' in lead II)?
  • Clinical Briefs By Louis Kuritzky, MD

    It has been customary to ask patients on warfarin, once controlled and stable, to return on a monthly basis for recheck.
  • Clinical Briefs By Louis Kuritzky, MD

    In most communities in the United States, hepatitis C (HEPc) treatment is provided by gastroenterologists. Because HEPc is now the most common cause of end-stage liver disease, and unless trends reverse will continue to be so for the foreseeable future, it is important that identification of HEPc infection be continued vigorously in the primary care community, since most at-risk persons see primary care clinicians as their point of initial contact with the health care system.
  • Does Being Obese Matter If You Have Medicare?

    In the Medicare population, obesity was not associated with mortality, except for those with a BMI of at least 35. However, both overweight and obesity were associated with new or worsening disability within 2 years.
  • Sleep Apnea and Perioperative Complications After Noncardiac Surgery

    In a population-based study using hospital discharge diagnosis codes, patients with sleep apnea who underwent knee arthroplasty or open abdominal procedures were more likely to require invasive mechanical ventilation and to be diagnosed with aspiration pneumonia or ARDS than were matched patients without sleep apnea. Knee-replacement patients, but not those undergoing laparotomy, also were more likely to be diagnosed with pulmonary embolism.
  • Linagliptin Tablets (Tradjenta™)

    A third dipetdyl peptidase-4 (dpp-4) inhibitor has been approved by the FDA. Linagliptin follows sitagliptin and saxagliptin to the market. It is marketed by Boehringer Ingelheim as Tradjenta.
  • Impact of Drug Class on Long-Term Adherence to Antihypertensives

    Important differences in adherence to antihypertensive drug therapy occurred depending on the drug class prescribed with the lowest adherence noted to occur with diuretics and beta-blocker therapy and the highest adherence was observed with ARB or ACI therapy.
  • Add Prunes to Your Toolkit for Constipation

    Dried plums (prunes) are safe and more effective than psyllium for treating mild-to-moderate constipation.
  • Something's Fishy – DHA and Prostate Cancer

    In a shocking series of findings, this well-done prospective study showed that in men older than age 55 years a higher proportion of serum omega-3 fatty acids, specifically DHA, actually may increase the risk for high-grade prostate cancer.