Infectious Disease General
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RSV Bronchiolitis Has Persisting Consequences for Some Children
Young children hospitalized with respiratory syncytial virus (RSV) infection are at increased risk of subsequent hospitalization during the following year and of increased need for outpatient healthcare.
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A Comparison of Ceftaroline and Daptomycin in Treatment of MRSA Bloodstream Infections
Ceftaroline is an acceptable alternative therapy for treatment of methicillin-resistant Staphylococcus aureus bacteremia.
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An Effective Oral Regimen for Rifampin-Resistant Tuberculosis
A multicenter, randomized, controlled, noninferiority clinical trial found a 24-week, all-oral regimen (bedaquiline, pretomanid, linezolid, and moxifloxacin) to be safe and effective for patients aged 15 years and older with rifampin-resistant tuberculosis.
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COVID Is Not ‘Just the Flu’
Among hospitalized patients requiring oxygen support at admission, COVID-19 was three times more fatal than was influenza.
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Inching Toward the Goal: Does Selective Decontamination of the Digestive Tract Have a Benefit for Patients on Mechanical Ventilation?
Two recent articles contribute to the ongoing discussion of whether selective decontamination of the digestive tract provides a mortality benefit for patients who are receiving mechanical ventilation.
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Medical Masks Compared to N95 Respirators for COVID-19 Prevention in Healthcare Workers
A multicenter, randomized, controlled study found that medical masks were noninferior to N95 respirators in their relative protection against COVID-19 among healthcare workers when worn while providing routine care to patients with suspected or confirmed COVID-19.
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Infectious Disease Alert Updates
Is Your Hospital Room Toxigenic?; Reduction of HOCDI — Gaming the System?
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Salmonella Gastroenteritis — The Risk of a Rapid, Accurate Diagnosis
Availability of molecular testing panel results that were positive for Salmonella in children led to increased hospital admissions, increased subsequent microbiologic testing, and increased antibiotic use — all without benefit to patients.
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Resistance of SARS-CoV-2 Variants to Monoclonal Antibodies
Prevalent SARS-CoV-2 variants are increasingly resistant to therapeutic and prophylactic monoclonal antibodies but remain susceptible to Paxlovid, remdesivir, and molnupiravir.
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The Dental Procedure-Infective Endocarditis Link Controversy Continues
Infective endocarditis was more common with dental surgery or tooth extractions in the preceding four weeks in high-risk patients. Researchers abrogated this risk with antibiotic prophylaxis before the procedure.