Neurology/Neurosurgery General
RSSArticles
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Essential Tremor and Dystonic Tremor: Similar Appearance but Different Cerebral Networks
Using MRI BOLD and seed-based functional connectivity, during a grip-force task, network-level connectivity was shown to be highly distinct between two otherwise phenotypically overlapping tremor types — dystonic tremor and essential tremor.
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Clinical Features of Subdural Fluid Collections With Intracranial Hypotension
Clinical features of patients with spontaneous intracranial hypotension and bilateral subdural fluid collections differ from patients who sustained previous head trauma vs. those with cerebrospinal fluid leaks.
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MRI Investigation of Brain Abnormalities in Friedreich’s Ataxia
Friedreich’s ataxia (FRDA) is characterized by progressive weakness, sensory loss, ataxia, and dysarthria starting in childhood. The authors of this MRI-based study demonstrated that structural damage is limited to the spinal cord, red nucleus, and cerebellar peduncles in young FRDA patients, but progresses to widespread cerebral damage in adult FRDA patients.
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Vasculitic Neuropathy: Improving Diagnostic Accuracy
SYNOPSIS: Vasculitic neuropathy is characterized by stepwise progression of sensorimotor neuropathy, usually with axonal features on electrodiagnostic studies, and often the presence of antimyeloperoxidase and rheumatoid factor antibodies and cryoglobulins. However, peripheral nerve biopsy is necessary for a definitive diagnosis.
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Zika-associated vs. Non-Zika Guillain-Barré Syndrome
Guillain-Barré syndrome associated with Zika virus is similar to non-Zika virus cases in terms of severity of illness and prognosis around long-term recovery and disability.
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A Possible New Treatment for HTLV-1-associated Myelopathy
Mogamulizumab reduces central nervous system inflammation and improves spasticity in patients with HTLV-1-associated myelopathy.
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Parsonage-Turner Syndrome: Where’s the Lesion?
SYNOPSIS: This careful analysis of MRI imaging of the brachial plexus in patients with well-defined Parsonage-Turner Syndrome showed that the lesions are in peripheral branches of the brachial plexus and not in the roots or cords.
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Pain in Anti-MAG Neuropathy
Most patients with anti-MAG neuropathy complain of painful paresthesias or dysesthesias, but unlike diabetic neuropathy, these symptoms are not severe and do not affect quality of life as much as motor weakness.
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Blockade of CGRP for Migraine Prevention: Promising, but Not a Cure
Blockade of calcitonin gene-related peptide in patients with chronic or episodic migraine results in the prevention of about two headache days a month compared to placebo.
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First-ever Study of Genome Sequencing in the Common Forms of Epilepsy
In the first study with genome sequencing in the common forms of epilepsy, ultra-rare genetic mutations of known epilepsy genes were over-represented in the epilepsy population, compared to controls.