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A consensus group making recommendations on the use of restraining therapies in the ICU emphasizes the inadequacy of the evidence base in this area and calls for studies to generate better data.
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This single-center study reveals that, compared to continuous sedation, daily sedative interruption is not associated with adverse psychological effects after 6-21 months.
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Adult patients presenting with acute asthma without significant respiratory acidosis who were given 100% oxygen to breathe had slight increases in arterial PCO2 and slight decreases in arterial pH and peak expiratory flow, as compared with patients who received only 28% oxygen.
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In late-onset VAP, survival improved and costs decreased using initial coverage with 3 antibiotics. Mini-BAL did not improve survival but decreased costs and antibiotic usage.
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This report from multiple cooperating centers describes findings in 403 patients who presented with dysphagia and 140 patients with noncardiac chest pain and 44 patients with both symptoms on presentation.
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This report by Song and colleagues used a validated food frequency questionnaire in 39,345 women from the Womens Health Study.
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Since the results of the Womens Health Initiative randomized trials, many fewer postmenopausal women are using estrogen to control hot flashes. Alternatives include progesterones, antidepressants in low doses, caffeine avoidance, exercise, phytoestrogens, and black cohosh.
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In heterozygous familial hypercholesterolemia patients, rosuvastatin produced significantly greater reductions in LDL cholesterol, increases in HDL cholesterol, beneficial changes in other lipid values, and achievement of NCEP cholesterol goals than observed with equivalent doses of atorvastatin, with a similar adverse event profile.
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The meta-analysis by Vink and colleagues demonstrates that patients with either aortic or mitral valve replacement will benefit from high-intensity VKA therapy.